ACTRI Seminar Series: Outbreakiomics Abstract: Our group is using viral genomics, computational biology, and immunological approaches to gain insights into how viruses emerge, spread, and evolve in human populations. We have applied our approach of “genomic epidemiology” to the study of multiple severe human pathogens, including West Vile virus, Zika virus, Ebola virus, and Lassa virus. Via these studies, we have, for example, shown how Zika virus were introduced into the United States multiple times from the Caribbean, and how Ebola virus spread during the West African epidemic while undergoing adaptive evolution.