Shifting the scholarly culture toward open access, open data, and open workflow is partly an incentives problem, partly an infrastructure problem, and partly a coordination problem. The Center for Open Science (COS) is a non-profit technology and culture change organization working on all three. Central elements of COS’s strategy are to provide policy, incentive, and normative solutions that are applicable across institution, funder, publisher, and society stakeholders, and to provide efficient implementations of those solutions with open-source public goods infrastructure that is branded and operated by the communities themselves (OSF). Brian Nosek is co-founder and executive director of the Center for Open Science, which operates the Open Science Framework. COS is enabling open and reproducible research practices worldwide. Brian is also a professor in the Department of Psychology at the University of Virginia. He received his Ph.D. from Yale University in 2002. He co-founded Project Implicit, a multi-university collaboration for research and education investigating implicit cognition–thoughts and feelings that occur outside of awareness or control. Brian investigates the gap between values and practices, such as when behavior is influenced by factors other than one’s intentions and goals. Nosek applies this interest to improve the alignment between personal and organizational values and practices. In 2015, he was named one of Nature’s 10 and to the Chronicle for Higher Education Influence list. For more information about the event, contact Serafin Raya at s1raya@ucsd.edu.