Overview: E-cigarettes have become popular and widely used so fast that the safety testing on them is practically non-existent. While researchers rush to define the toxicities and potential health effects of e-cigarettes, should we be advising everyone against these nicotine delivery devices? Or should we try to be positive and hopeful, in case e-cigarettes have fewer adverse health effects relative to conventional tobacco cigarettes, and thus advise current smokers to switch to e-cigs as a harm reduction strategy? Beyond that, what are the risks of the different e-cig flavors and types of devices? Is vaping caffeine and THC more or less dangerous than vaping nicotine? What are the specific dangers of e-cig use for children, teenagers and young adults? Guest Speaker: Dr. Laura E. Crotty Alexander, M.D., Associate Professor of Medicine at the University of California San Diego and a staff physician and researcher at the VA San Diego Healthcare System, Dr. Crotty is a pulmonary critical care specialist with clinical and research-based interests in e-cigarettes. She studies the effects of cigarette smoke and e-cigarette vapor on bacterial virulence, as well as the effects of e-cigarettes on airway inflammation and innate immune function. Dr. Crotty Alexander is a graduate of Duke University School of Medicine, completed residency at Massachusetts General Hospital, the Harvard Pulmonary Critical Care Fellowship Program, and a postdoctoral fellowship in Host Defense and Bacterial Virulence at UCSD.