Southern California Stem Cell Seminar Series, August Speaker, Luis FZ Batista, PhD
Talk Title:
“Targeted Differentiation of Human Embryonic Stem Cells Help Identify Novel Targets in Patients with Impaired Assembly of Telomerase and the Spliceosome”
Professor, Pediatrics, Cellular & Molecular MedicineUC San Diego Health
Director, UC San Diego Stem Cell Program
Lab Website
Lab Research
The overarching goal of my research is to understand the importance of telomerase in human stem and progenitor cell function and regulation. I am interested in understanding how genetic instability leads to diminished pluripotent cell function over time and how it influences tissue homeostasis, human aging and cancer. My laboratory uses genome-wide methods to uncover alterations that drive cellular failure upon critical telomere dysfunction, using human pluripotent cells as a primary model. We combine in vitro biochemical and mechanistic studies with our ability to generate and differentiate pluripotent cells to better understand the importance of telomere maintenance in this process and to determine the events that lead from telomere dysfunction to human disease.
Seminar Objective
Stem Cell Program was founded on the unique strengths of the UC San Diego research community, with its unparalleled cross-disciplinary collaborations and strong basic and comparative biomedical science programs.
The University of California, San Diego Stem Cell Seminar Series is intended to stimulate the exchange of experience with researchers outside of UC San Diego, enhance interactions with sister institutions and biomedical campuses, and promote education in stem cell research.
The monthly Stem Cell Seminar Series brings scientists from all over the world to the forefront of regenerative medicine and emphasizes the basic research and translational themes of stem cell research. These seminars provide an opportunity for the “Mesa” community to learn about the work being done by prestigious researchers from other institutions, preview unpublished scientific results, initiate collaborations and build networks. The speakers invited provide novel insights into stem cell functions, tissue development, and cell-based approaches for the treatment of diseases.
Goals
We strive to promote unparalleled cross-disciplinary collaborations and strong basic and comparative biomedical science programs and support development of essential core facilities and facilitate training and educational activities.
Solution
These goals are accomplished through presentations by distinguished invited speakers from various avenues of stem cell research and by poster presentations by graduate students and post-docs.